Two different cases of episodic angioedema with eosinophilia.
- Author:
Chan Sun PARK
1
;
Seong Suk LEE
;
Jeong Woo LIM
;
Jung Min AN
;
Tae Hoon LEE
;
You Sook CHO
;
Hee Bom MOON
Author Information
1. Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. hbmoon@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Angioedema;
Eosinophilia
- MeSH:
Angioedema*;
Diagnosis;
Eosinophilia*;
Fever;
Humans;
Hypereosinophilic Syndrome;
Japan;
Prognosis;
Weight Gain
- From:Korean Journal of Medicine
2005;69(6):706-710
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Episodic angioedema with eosinophilia (Gleich's syndrome) is characterized by recurrent angioedema, fever, weight gain and peripneral eosinophilia. The symptoms and clinical course differ markedly from the idiopathic hypereosinophilic syndrome, including an absence of end organ involvement and a better prognosis. A transient variant, mainly reported in Japan, which is limited to a single attack, is usually less severe than the episodic type. Here we describe two young patients, one of those is the episodic type and the other is the transient type. We suggest that episodic angioedema with eosinophilia is not rare, and should be widely recognized as a new clinical entity for accurate and prompt diagnosis. Awareness and distinction from the hypereosinophilic syndrome is important because of the favorable prognosis and rapid response to corticosteroid therapy.
