Effect comparison between laparoscopic surgery and laparotomy surgery on coagulation function in patients with gastric cancer
- VernacularTitle:腹腔镜胃癌手术与开腹手术对凝血功能的影响对比
- Author:
Hui JIANG
1
;
Jun DU
;
Jiming GU
;
Qizhong GAO
;
Liugen JIN
;
Bojian FEI
Author Information
- Keywords: laparoscopic surgery; gastric cancer; prothrombin time; activated partial thromboplastin time; fibrinogen; D-dimer
- From: Journal of Clinical Medicine in Practice 2014;(17):155-157
- CountryChina
- Language:Chinese
- Abstract: Obj ective To investigate the effects of laparoscopic surgeryon coagulation func-tion in patients with gastric cancer.Methods A total of 71 patients with gastric cancer were divid-ed into laparoscopic group and laparotomy group.Levels of D-dimer (D-D)and fibrinogen (FIB), prothrombin time (PT),activated partial thromboplastin time (APTT)were detected before opera-tion,end of operation and 24 hours after operation.Prothrombin time-international normalized ratio (INR)was calculated and coagulation function was observed in both groups.Results There were no significant differences in APTT and INR before and after operation in both groups (P>0 .05 ). PT at 24 hours after operation was significantly shorter than that before operation(P<0 .05 ),but there was no significant difference between two groups (P>0 .05 ).Levels of FIB and D-D in-creased after operation,and there were significant differences between two groups (P<0 .05 ). Conclusion Blood hypercoagulability and potential thrombosis are associated with patients with la-paroscopic surgery or laparotomy surgery.Preventions during preoperative period should be conduct-ed to mitigate the effects of laparotomy surgery on coagulation function.
