Effect of sodium phosphocreatine on myocardial protection of patients with paroxysmal supraventricular tachycardia by treatment of radiofrequency catheter ablation
10.7619/jcmp.201409003
- VernacularTitle:磷酸肌酸钠对阵发性室上性心动过速经导管射频消融术的心肌保护作用
- Author:
Xiaohui TAN
1
;
Jieqiang LIU
;
Yizhi LUO
;
Zhuanhe LIANG
;
Keyun ZHU
Author Information
1. 南方医科大学附属新会医院
- Keywords:
sodium phosphocreatine;
paroxysmal supraventricular tachycardia;
radiofre-quency catheter ablation;
myocardial protection
- From:
Journal of Clinical Medicine in Practice
2014;(9):11-14,18
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of sodium phosphocreatine (SPC)on myocardi-al protection of patients with paroxysmal supraventricular tachycardia (PSVT)by treatment of radiofre-quency catheter ablation (RFCA).Methods 40 patients with PSVT by treatment of RFCA were ran-domly divided into SPC group (daily intravenous drip of 1 g SPC in 250 ml of normal saline,n =20) and NS group (the same volume of NS only,n =20).Assessment parameters that serum creatine ki-nase (CK),creatine kinase isoenzyme-MB (CK-MB)and cardiac troporin T (cTn T)were temporally investigated from pre-to 72 h after RFCA.Additionally,SPC-related adverse events were recorded. Results Compared with NS group,the overall and peak serum CK,CK-MB and cTn T significantly decreased in SPC group (P <0.05)during 24 hours after RFCA.No SPC-related adverse events were observed.Conclusion SPC shows a myocardial protective effect in patients with PSVT by treatment of RFCA.
