Treatment with Rituximab in a Patient with Refractory Felty Syndrome and Low Rheumatoid Arthritis Disease Activity: A Case Report.
- Author:
Sung Hae CHANG
1
;
Ji Ae YANG
;
Sang Jin LEE
;
Jun Won PARK
;
Kichul SHIN
;
Eun Bong LEE
;
Yeong Wook SONG
;
Eun Young LEE
Author Information
- Publication Type:Case Report
- Keywords: Felty syndrome; Rituximab; Rheumatoid arthritis
- MeSH: Antirheumatic Agents; Arthritis; Arthritis, Rheumatoid*; Felty Syndrome*; Humans; Neutropenia; Splenomegaly; Rituximab
- From:Journal of Rheumatic Diseases 2014;21(1):35-39
- CountryRepublic of Korea
- Language:Korean
- Abstract: Felty syndrome (FS) is a rare manifestation in rheumatoid arthritis (RA) characterized by neutropenia and splenomegaly. Treatment for FS is not well established because there has been no randomized controlled study. A few recent reports found rituximab effective in patients with refractory FS. According to those reports, most patients with RA and FS had active arthritis. Here we report a case of a patient with glucocorticoid dependent and disease-modifying anti-rheumatic drugs (DMARDs) refractory FS and quiescent RA who was successfully treated with rituximab.
