Progress and clinical applications of biodegradable collagen stimulator-based compound injectables
10.3760/cma.j.cn114453-20211231-00493
- VernacularTitle:基于可生物降解胶原刺激材料的复合性注射产品的研究进展和临床应用
- Author:
Zonglin HUANG
1
;
Anna LIU
;
Zhonglin HU
;
Baozhen SHAN
;
Xuefeng HAN
Author Information
1. 中国医学科学院北京协和医学院整形外科医院脂肪整形科，北京 100144
- Keywords:
Injections;
Facial rejuvenation;
Poly-L-lactic acid;
Polycaprolactone;
Polymer fillers
- From:
Chinese Journal of Plastic Surgery
2023;39(9):1039-1042
- CountryChina
- Language:Chinese
-
Abstract:
Volume loss caused by aging process, diseases, trauma and surgical treatments, could lead to facial depressions, profoundly affecting appearance. Injectable fillers could help to correct this type of disfigurements and are preferred by plastic surgeons and patients due to their quality of minimal invasiveness and better delicateness. Among these fillers, collagen stimulators such as poly-L-lactic acid(PLLA) and polycaprolactone(PCL) are biodegradable synthetic polymers that can stimulate collagen formation and thus gradually restore tissue volume. These polymers have been used worldwide to treat facial aging changes and human immunodeficiency virus-associated facial fat lipoatrophy, demonstrating ideal results in volume enhancement and facial rejuvenation. The progress and clinical applications of compound injectables based on biodegradable collagen stimulators are summarized.
