The Correlation of Dyspnea and Radiologic Quantity in Patients with COPD.
10.4046/trd.2009.66.4.288
- Author:
Eun Jung JUNG
1
;
Yang Ki KIM
;
Young Mok LEE
;
Ki Up KIM
;
Soo Taek UH
;
Yong Hoon KIM
;
Do Jin KIM
;
Choon Sik PARK
;
Jung Hwa HWANG
Author Information
1. Division of Respiratory and Allergy Medicine, Soonchunhyang University Hospital, College of Medicine, Seoul, Korea. uhs@hsop.sch.ac.kr
- Publication Type:Original Article
- Keywords:
Dyspnea;
Chronic obstructive pulmonary disease;
Radiology
- MeSH:
Diaphragm;
Dyspnea;
Emphysema;
Forced Expiratory Volume;
Humans;
Lung;
Pulmonary Disease, Chronic Obstructive;
Spirometry;
Thorax
- From:Tuberculosis and Respiratory Diseases
2009;66(4):288-294
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: A lung hyperinflation, or air trapping, caused by expiratory flow-limitation contributes to dyspnea in patients with chronic obstructive pulmonary disease (COPD). Forced expiratory volume in 1 second (FEV1) has served as an important diagnostic measurement of COPD, but does not correlate with patient-centered outcomes such as dyspnea. Therefore, this study was performed to investigate the role of radiologic quantity in evaluating the dyspnea in patients with COPD by measuring lung hyperinflation in chest x-ray and high resolution chest tomography (HRCT). METHODS: Fifty patients with COPD were enrolled in this study. Their subjective dyspnea score (modified Borg scale dyspnea index), spirometry, and lung volume were measured. Simultaneous hyperinflations of chest x-ray score ("chest score") and degree of emphysema of HRCT ("HRCT score") were measured. The "chest score" were composed of lung length, retrosternal space width, and height of the arc of the diaphragm and "HRCT score" were composed of severity and extent of emphysema. RESULTS: The mean age of patients was 69 years old and their mean FEV1 was 51.7%. The Borg score significantly correlated with parameters of spirometry and lung volume, including FVC, FEV1, FEV1/FVC, RV, RV/TLC, and DLCO. The Borg score correlated well with "HRCT score", but did not correlate with "chest score". Also, the Borg scale correlates inversely with body mass index. CONCLUSION: The quantity of emphysema on chest HRCT may serve as an objective marker of dyspnea in patients with COPD.
