The research progress of immunoregulatory mechanism of immune cells in hypertrophic scar formation
10.3760/cma.j.cn114453-20211101-00428
- VernacularTitle:免疫细胞在增生性瘢痕形成中免疫调控机制的研究进展
- Author:
Wen ZHAO
1
;
Rongtao CUI
Author Information
1. 山东第一医科大学附属省立医院烧伤整形外科，济南 250021
- Keywords:
Cicatrix;
Hypertrophic scar;
Immune cells;
Immune molecules;
Natural killer cells;
Immunotherapy
- From:
Chinese Journal of Plastic Surgery
2023;39(8):907-915
- CountryChina
- Language:Chinese
-
Abstract:
Hypertrophic scar(HS) is the result of abnormal hyperplasia of local tissue repair after trauma, which commonly proliferates and relapses. The scars affect the beauty or lead to dysfunction. It has always been a major problem for clinical doctors. This review summarized the mechanisms of different immune cells and their immune molecules in the process of wound healing and scar formation, and sketched the existing hypertrophic scar immunotherapies to provide references for researchers to further study HS.
