Research progress of long non-coding RNA H19 in fibrotic diseases
10.3760/cma.j.cn114453-20200329-00186
- VernacularTitle:长链非编码RNA H19在纤维化疾病中的研究进展
- Author:
Hong YUAN
1
;
Maopeng LIU
;
Jie ZHANG
Author Information
1. 南昌大学第一附属医院口腔颌面外科，南昌 330006
- Keywords:
Long non-coding RNA H19;
Fibrosis;
Fibroblasts;
Extracellular matrix;
Epithelial-mesenchymal transition
- From:
Chinese Journal of Plastic Surgery
2022;38(4):457-462
- CountryChina
- Language:Chinese
-
Abstract:
Fibrotic diseases often cause damage to multiple tissues and organs, which still lack an effective therapy. At present, it has been found that long non-coding RNA(LncRNA) H19 is differentially expressed in fibrosis of skin, liver, lung, heart, kidney, and other organs, indicating that LncRNA H19 may be involved in the occurrence and development of fibrotic diseases.This article summarizes the relationship between LncRNA H19 and the development of fibrotic diseases and its role in various organs, which provides a new idea for the diagnosis, prevention, and treatment of fibrotic diseases.
