Progress in the treatment of diabetic foot with mesenchymal stromal cell therapy
10.3760/cma.j.cn114453-20201023-00545
- VernacularTitle:间充质干细胞疗法治疗糖尿病足的研究进展
- Author:
Xinyu LIU
1
;
Tingrui ZHAO
;
Mogen ZHANG
;
Zhaohui ZHAI
;
Yuli LI
Author Information
1. 潍坊医学院临床医学院 261053
- Keywords:
Diabetic foot;
Wound healing;
Diabetes mellitus;
Mesenchymal stromal cells
- From:
Chinese Journal of Plastic Surgery
2021;37(12):1404-1409
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes has become a chronic disease endangering people’s health all over the world. This translated into a huge economic burdento society. Diabetic foot ulcer is difficult to heal due to ischemia, infection, neuropathy and other reasons, which leads to increased risk of amputation and infectious death. Amputation is the main method in traditional treatment, which is adverse to improve the quality of patients’ lives. Thus, more and more scientists pay attention to the treatment of diabetic foot with mesenchymal cells. In this article, we will give a general introduction to the multi-functional mesenchymal stromal cells and explain the mechanism of their use in diabetic foot ulcer, as well as introduce several cases of clinical and preclinical studies on the application of mesenchymal cells in the treatment of diabetes ulcers in foreign countries.
