Research progress on the effect of adipocytes on breast cancer development and treatment
10.3760/cma.j.cn114453-20200413-00219
- VernacularTitle:脂肪细胞在乳腺癌发展及治疗中的相关作用机制研究进展
- Author:
Chongru ZHAO
1
;
Mingchen XIONG
;
Qi ZHANG
;
Yiping WU
Author Information
1. 华中科技大学同济医学院附属同济医院整形美容外科，武汉 430030
- Keywords:
Adipocytes;
Breast neoplasms;
Cancer-associated adipocyte;
Breast reconstruction
- From:
Chinese Journal of Plastic Surgery
2021;37(10):1186-1191
- CountryChina
- Language:Chinese
-
Abstract:
The occurrence and development of breast cancer depend on the reciprocal effects between breast cancer cells and tumor microenvironment. Adipocytes are not only the component of breast interstitial cells, but also an important part of the tumor microenvironment in breast cancer. Among them, cancer-associated adipocytes, which are located at the invasive front of breast cancer, participate in the progression and metastasis of breast cancer by secreting multiple active factors and related mechanisms. The authors made a brief review on the mechanisms related to the development and therapeutic effects of adipocytes on breast cancer.
