Quantitative assessment for bone resorption following cranial remodeling in children and adolescent congenital cranial deformity cases
10.3760/cma.j.cn114453-20200508-00274
- VernacularTitle:儿童及青少年先天性头颅畸形颅骨重塑和牵张成骨后骨吸收的定量分析
- Author:
Yingnan GENG
1
;
Zheyuan YU
;
Liang XU
;
Huichuan DUAN
;
Min WEI
;
Jie YUAN
Author Information
1. 上海交通大学医学院附属第九人民医院整复外科 200011
- Keywords:
Bone resorption;
Skull;
Bone transplantation;
Congenital cranial deformity
- From:
Chinese Journal of Plastic Surgery
2021;37(2):158-161
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To quantitatively assess the degree of bone resorption following cranial bone remodeling for children and adolescent congenital cranial deformity cases in Crouzon syndrome.Methods:A total of 14 congenital cranial deformity patients (mean age 7.7 years) who underwent cranial bone remodeling between Mar. 2014 and Dec. 2018 were selected from Shanghai Ninth People’s Hospital, and retrospectively reviewed. They were treated with modified monobloc osteotomy and distraction osteogenesis. Craniectomy and cranial bone remodeling were performed, and the follow-up period was one week(t1) and one year(t2). The patients were scanned by spiral CT at the two following time points. Then data were imported into Mimics to acquire the three-dimensional model of skull. Bone volume was measured with Mimics Research 18.0 after three-dimensional CT reconstruction. The resorption rate was calculated as (V t1-V t2)/V t1×100%(V t1 represented bone volume before distraction osteogenesis, V t2 represented bone volume after distraction osteogenesis), followed by statistical analysis. Results:Among the 14 patients, bone resorption occurred in 11 patients and the resorption rate after 1 year was 3.482%. There was no significant difference between bone volumes at 1 week and 1 year after surgery( t=0.851, P=0.410). Conclusions:Bone resorption following cranial bone remodeling for children and adolescents with congenital cranial deformity did exist, however, it was acceptable. Therefore, the surgical treatment of cranial remodeling and distraction osteogenesis is advisable for children and youth with congenital cranial deformities over 1 year old.
