The experimental research on osteogenesis in width augmentation of the mandibles with a sandwich-osteotomy with interpositional natural coral and coralline hydroxyapatite
10.3760/cma.j.cnZHZXWKZZ-2018-1107-00449
- VernacularTitle:天然珊瑚石和珊瑚羟基磷灰石夹心法对下颌骨厚度扩展中成骨的影响
- Author:
Wuyuan TAN
1
;
Ying CHEN
;
Meng WANG
;
Jianfeng LIU
;
Feng NIU
;
Bing YU
;
Lai GUI
Author Information
1. 中南大学湘雅医院整形美容科，长沙 410008
- Keywords:
Sandwich osteotomy;
natural coral;
Coralline hydroxyapatite;
Osteogenesis
- From:
Chinese Journal of Plastic Surgery
2020;36(4):447-452
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the influence on osteogenesis during mandibular augmentation with a new sandwichosteotomy with interpositional natural coral and coralline hydroxyapatite (CHA).Methods:Nine goats were randomly divided into three groups and observed at 6 months, 12months and 18 months after surgery. All goats received splitting of bilateralmandibular outer cortex and interpositional grafting with natural coral and corallinehydroxyapatite respectively (sandwich osteotomy). Partial mandible in each group had been harvested to do histology examination(HE staining and Toluidine blue staining) and ultrastructure analyses (Scanning electron microscope, SEM).Results:All subjects were evaluated atdifferent time points. Both natural coral and coralline hydroxyapatite side healed at three groups. Natural coral were degraded at about 6 months postoperation, coralline hydroxyapatite at about 12 months. The results of HE staining, Toluidine blue staining and SEM revealed that natural coral side had better osteogenesis than coralline hydroxyapatite side at 6 months after operation.However, Natural coral and coralline hydroxyapatite side had no significant differences at 12 and 18months.Conclusions:This study suggests an alternative method for mandibular augmentation witha sandwich osteotomy and interpositional grafting with natural coral and CHA.Bothcoral hydroxyapatite and natural coral have good osteogenesic effect for mandibular augmentation.
