Clinical study of radiofrequency ablation combined with lauromacrogol for the treatment of parotid gland hemangioma in infants
10.3760/cma.j.issn.1009-4598.2016.04.004
- VernacularTitle:射频消融联合聚桂醇注射治疗婴幼儿腮腺血管瘤的临床研究
- Author:
Tao HAN
1
;
Haini CHEN
;
Jijun ZOU
;
Yi JI
;
Jianbing CHEN
;
Weimin SHEN
;
Jie CUI
Author Information
1. 210008,南京医科大学附属南京儿童医院烧整外科
- Keywords:
Radiofrequency ablation;
Lauromacrogol;
Parotid gland;
Hemangioma
- From:
Chinese Journal of Plastic Surgery
2016;32(4):254-258
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of radiofrequency ablation (RFA) combined with lauromacrogol for the treatment of parotid gland hemangioma in infants.Methods From Sep.2005 to Dec.2014,a total of 117 patients with parotid gland hemangioma were divided into observation group (n =32),control group 1 (n =30),control group 2 (n =28) and control group 3 (n =27).The observation group was treated by RFA combined with lauromacrogol,while the control group 1 was treated by RFA only,the control group 2 was treated by pingyangmycin only,and the control group 3 received additional pingyangmycin based on RFA.All the patients were followed up for 6 to 24 months,and the clinical effects were observed in four groups.Results Control group 1:16 patients were cured (53.3％),and the number of patients with ≥2 treatments was 9.There was 1 case with skin ulceration,1 with abdominal discomfort,1 with liver function damage and 1 with high fever.Control group 2:17 patients were cured(60.7％),and number of patients with ≥2 treatments was 12.There were 3 cases with skin ulceration,9 with abdominal discomfort,6 with liver function damage and 5 with high fever.Control group 3:21 patients were cured(77.8％),and number of patients with ≥2 treatments was 2.There were 2 cases with skin ulceration,6 with abdominal discomfort,4 with liver function damage and 4 with high fever.However,in observation group,25 patients were cured(78.1％) and number of patients with ≥ 2 treatments was 4,which were significantly different from that in control group 1 or control group 2 (P ＜0.05).And the difference in postoperative adverse reactions between observation group and control group 2 or control group 3 was also of significance (2 with skin ulceration,1 with abdominal discomfort,1 with liver function damage and 6 with high fever,P ＜ 0.05).Conclusions Combined RFA and lauromacrogol has a good therapeutic effect on parotid gland hemangioma with relatively low adverse effect,so it deserves to be suggested and applied in clinical practice.
