A Case of Diffuse Leukoencephalopathy Caused by 5-Fluorouracil.
- Author:
Yoo Mi PARK
1
;
Hye Young KWON
;
Hoo Won KIM
;
Dong Kwon KIM
Author Information
1. Department of Neurology, Taejon, Eulji Hospital, Korea.
- Publication Type:Case Report
- MeSH:
Brain;
Carcinoid Tumor;
Cerebrospinal Fluid;
Cerebrum;
Dementia;
Dysarthria;
Fluorouracil*;
Gait;
Intestines;
Leukoencephalopathies*
- From:Journal of the Korean Neurological Association
1995;13(4):1007-1010
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
5-Fluorouracil is one of the most commonly used anticancer drug. We report a case of leukoencephalopathy who had received 5-fluorouracil injection following operation of carcinoid tumor in intestine. The case had dementia, dysarthria and gait disturbance. Brain CT showed bilaterally symmetric diffuse low densities in the white matter of cerebrum and cytologic examination of cerebrospinal fluid was negative for malignancy. Discontinuation of 5- fluorouracil injection for several days and then improved the clinical symptoms.
