Detection of colorectal advanced neoplasms among the cancer screening population in urban areas of Henan Province and analysis on its influencing factors
10.3760/cma.j.cn112152-20231026-00272
- VernacularTitle:河南省城市地区结肠镜筛查人群结直肠进展期肿瘤检出情况及其影响因素分析
- Author:
Lanwei GUO
1
;
Liyang ZHENG
;
Qiong CHEN
;
Yin LIU
;
Huifang XU
;
Ruihua KANG
;
Hong WANG
;
Xiaoyang WANG
;
Shuzheng LIU
;
Shaokai ZHANG
Author Information
1. 郑州大学附属肿瘤医院 河南省肿瘤医院 河南省肿瘤防控工程研究中心 河南省肿瘤预防国际联合实验室 河南省肿瘤防治研究办公室，郑州450008
- Keywords:
Colorectal neoplasms;
Colonoscopy;
Screening;
Influencing factors;
Henan Province
- From:
Chinese Journal of Oncology
2024;46(8):794-800
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the detection of colorectal advanced neoplasms in the population who underwent colonoscopy screening in Henan Province as part of the Urban China Cancer Screening Program and its influencing factors.Methods:A cross-sectional study design was employed. Based on the Cancer Screening Program conducted in Henan Province, the study enrolled 7 454 urban residents who manifested no symptoms and were recruited from eight cities in the province, including Zhengzhou, Zhumadian, Anyang, Luoyang, Nanyang, Jiaozuo, Xinxiang, and Puyang from October 2013 to October 2019, and participated in colonoscopy screening. The χ 2 test was used to compare the detection rates of colorectal advanced neoplasms among participants with different characteristics, and a multivariate logistic stepwise regression model was used to analyze the factors affecting the detection rates. Results:A total of 7 454 subjects underwent colonoscopy screening, and 112 cases of colorectal advanced neoplasms were detected. Multivariate logistic regression analysis suggested that older age, smoking, higher meat intake, history of diabetes, and family history of colorectal cancer in a first-degree relative were risk factors for colorectal advanced neoplasms. The detection rate was significantly higher in people aged 60-74 years compared with those aged 40-49 years, with an odds ratio ( OR) of 2.04 (95% CI: 1.23-3.38).The rates were higher in people who smoked than those who did not smoke, with an OR of 2.21 (95% CI: 1.48-3.31), and in people who consumed more meat than those who consumed less, with an OR of 1.53 (95% CI: 1.04-2.26). Those with diabetes had a higher detection rate compared with those without, with an OR of 1.69 (95% CI: 1.07-2.69), and those with a first-degree family history of colorectal cancer had a higher detection rate than those without, with an OR of 1.64 (95% CI: 1.09-2.46). Conclusion:The detection rate of colorectal advanced neoplasms through colonoscopy screening in Henan Province covered by the Urban China Cancer Screening Program is 1.50%. Older age, smoking, higher meat intake, history of diabetes, and family history of colorectal cancer in a first-degree relative are identified as risk factors for colorectal advanced neoplasms.
