Progress in risk factors and potential biomarkers of esophageal squamous cell carcinoma

VernacularTitle:食管鳞状细胞癌危险因素与潜在分子标志物研究进展
Author: Jiachen ZHOU ¹ ; Ru CHEN ; Guihua ZHUANG ; Wenqiang WEI
Author Information

1. 西安交通大学医学部公共卫生学院流行病与卫生统计学系　710061
Keywords: Esophageal neoplasms; Squamous cell carcinoma; Risk factor; Biomarkers
From: Chinese Journal of Oncology 2021;43(12):1223-1227
CountryChina
Language:Chinese
Abstract: Esophageal cancer is the main malignant cancer in China. In 2015, the incidence and mortality of esophageal cancer were 17.87 per 100 000 and 13.68 per 100 000, respectively, ranking 6th and 4th in the incidence and death. Esophageal squamous cell carcinoma (ESCC) is the main pathological type of esophageal cancer, accounting for 86.3% of new cases. ESCC′s pathogenesis is still not clear and its related risk factors remain to be explored. There are no detection biomarkers that can be widely applied in the whole country nowadays. In order to provide a scientific basis for exploring the pathogenesis of ESCC and improve screening technology, this paper summarizes the research status of various risk factors and potential biomarkers of ESCC.