Progress in diagnosis and treatment of lung adenocarcinomas imaging manifesting as radiological part-solid nodule
10.3760/cma.j.cn112152-20200710-00646
- VernacularTitle:影像学表现为部分实性结节肺腺癌的诊断和治疗进展
- Author:
Guangyu BAI
1
;
Bin QIU
;
Ying JI
;
Peng SONG
;
Fan ZHANG
;
Qi XUE
;
Shugeng GAO
Author Information
1. 国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院胸外科 100021
- Keywords:
Lung neoplasms;
Part solid nodule;
Diagnosis;
Treatment
- From:
Chinese Journal of Oncology
2021;43(7):743-750
- CountryChina
- Language:Chinese
-
Abstract:
The incidence and mortality of lung cancer ranked the first in China. China had 787, 000 new cases of lung cancer in 2015, and a majority of these patients with advanced lung cancer. With the development and popularization of high-resolution computed tomography, more and more early-stage lung adenocarcinomas are found in screening. The imaging finding of early-stage lung adenocarcinomas often manifests as part solid nodule (PSN) containing ground glass opacity (GGO). Although the imaging manifestation of the nodules can′t accurately predict the pathologic type of nodules, the parts of solid nodule and GGO still have some pathologic indications, and the prognostic evaluation effect of the maximum diameter of PSN is superior to that of the whole nodule. With the development of the molecular radiography and molecular pathology, the relationship of imaging manifestation of the PSN and metastasis were focused on. Some PSNs with special nature are more active and rapidly progressed than the pure GGOs. While compared to the pure solid nodules, the aggressiveness of PSNs are insufficient, with lower metastatic rates of lymph node and better prognoses. Currently, international acknowledge recommends to take active intervention measure for PSNs which are highly suspected to be malignant. We focus on the diagnosis and treatment of PSNs, systemically depict their staging, follow-up, surgical treatment, gene detection and immunotherapy.
