Clinicopathological characteristics and outcomes of 122 patients with colorectal cancer metastasize to the ovary
10.3760/cma.j.cn112152-20200601-00504
- VernacularTitle:122例结直肠癌卵巢转移患者的临床病理特征及预后
- Author:
Qun LI
1
;
Yiqun LI
;
Honggang ZHANG
;
Chi YIHEBALI
;
Xingyuan WANG
;
Lin YANG
;
Aiping ZHOU
;
Yan SONG
;
Yongkun SUN
;
Jinwan WANG
;
Lingying WU
;
Jing HUANG
Author Information
1. 国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院内科 100021
- Keywords:
Colorectal neoplasms;
Ovarian metastasis;
Oophorectomy;
Prognosis
- From:
Chinese Journal of Oncology
2021;43(1):132-136
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinicopathological characteristics and prognosis of patients with ovarian metastases from colorectal cancer.Methods:A total of 122 female patients with ovarian metastases from colorectal cancer underwent treatment in Cancer Hospital, Chinese Academy of Medical Sciences between 2010 and 2015 were recruited. The clinicopathological features, treatment details and survival data of these patients were retrospectively analyzed. Kaplan-Maier method was used for survival analysis, log rank test and Cox proportional hazards model were used for prognostic factor analysis.Results:The median overall survival (OS) was 19.7 months. The 1-year, 3-years and 5-years OS rates were 72.1%, 24.7% and 9.9%, respectively. A total of 99 (81.1%) patients underwent oophorectomy. The median OS of patients who underwent oophorectomy was 21.9 months, significantly longer than 10.3 months of patients without oophorectomy ( P<0.01). Ovary as the only site of metastasis, primary tumor resection, and oophorectomy were associated with improved survival (all P<0.01). Primary tumor resection and oophorectomy were independent prognostic factors for OS (both P<0.01). Conclusion:Patients with ovarian metastases from colorectal cancer might acquire a survival benefit from surgical resection of the primary tumor and ovaries.
