Lymphoepithelioma-like hepatic carcinoma: the current status and progress

VernacularTitle:肝淋巴上皮瘤样癌的研究进展
Author: Changcheng TAO ¹ ; Kai ZHANG ; Weiqi RONG ; Jianxiong WU
Author Information

1. 国家癌症中心　国家肿瘤临床医学研究中心　中国医学科学院北京协和医学院肿瘤医院肝胆外科　100021
Keywords: Liver neoplasms; Lymphoepithelioma-like carcinoma; Status and progress
From: Chinese Journal of Oncology 2020;42(12):996-1000
CountryChina
Language:Chinese
Abstract: Lymphoepithelioma-like hepatic carcinoma (LELC) is a rare distinctive variant of liver cancer with unique epidemiological and pathological characteristics, characterized by dense lymphocyte infiltration.It can be divided into lymphoepithelioma-like hepatocellular carcinoma (LEL-HCC) and lymphoepithelioma-like cholangiocarcinoma (LEL-CC). The diagnosis is mainly based on pathology, and the treatment is mainly surgery. The prognosis of LELC is good, which may be related to a large number of lymphocyte infiltration. The data of LELC is very limited, only a few case reports and small retrospective studies, which needs further exploration and research. Up to now, 67 cases of LEL-HCC and 34 cases of LEL-CC have been reported. The purpose of this review is to provide a comprehensive overview of the current research situation on LELC in terms of epidemiology, clinical treatment, pathology and research prospects.