Incidental internal mammary lymph node biopsy in 113 cases of breast cancer undergoingfree abdominal flap breast reconstruction and its influencing factors
10.3760/cma.j.issn.0253-3766.2016.10.012
- VernacularTitle:113例乳腺癌游离腹部皮瓣乳房重建术机会性内乳淋巴结活检情况及其影响因素
- Author:
Chenlian QUAN
1
;
Naisi HUANG
;
Benlong YANG
;
Yan WANG
;
Ayong CAO
;
Yingying ZHANG
;
Xiaoyan HUANG
;
Jiajian CHEN
;
Zhenzhou SHEN
;
Zhimin SHAO
;
Jiong WU
Author Information
1. 200032,复旦大学附属肿瘤医院乳腺外科 复旦大学上海医学院肿瘤学系
- Keywords:
Breast neoplasms;
Biopsy,needle;
Lymph nodes;
Mammaplasty
- From:
Chinese Journal of Oncology
2016;38(10):769-773
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim of the current study is to determine the clinical value of incidental internal mammary lymph node biopsy in free abdominal flap breast reconstruction using internal mammary vessels as recipient vessels and to investigate the risk factors of internal mammary lymph nodes metastasis. Methods The clinical data of all patients who underwent free abdominal flap breast reconstruction using internal mammary vessels as recipient vessels from November 2006 to December 2015 in the Department of Breast Surgery, Fudan University Shanghai Cancer Center were reviewed in the study. The incidence of internal mammary lymph node biopsy and the rate of metastasis were analyzed. Statistical analysis was conducted to evaluate the risk factors of internal mammary lymph node metastasis. Results A total of 113 patients met the inclusion criteria, 53 (46.9%) of whom had internal mammary lymph nodes harvested. Four of these were positive for metastatic disease, all in immediate breast reconstructions. The incidence of metastasis was 7.5% in patients who had successful internal mammary lymph node biopsies.The multi?variate Logistic regression analysis showed that invasive tumor size, tumor location and axillary lymph node metastasis were not risk factors for internal mammary lymph node metastasis ( P>0. 05 ) . Conclusions Internal mammary lymph nodes found incidentally during recipient vessel exposure may provide important information about internal mammary lymph node metastasis in free flap breast reconstruction. This approach for internal mammary lymph node biopsy reveals an appreciable success rate and is convenient in clinical practice. The size of invasive tumor and the axillary lymph node metastasis are probably associated with internal mammary lymph node positivity.
