A retrospective cohort study of 302 thousand subjetc s of colorectal cancer screening in Haining City
10.3760/cma.j.issn.0253-3766.2015.04.016
- VernacularTitle:海宁市32万余结直肠癌筛查目标人群回顾性队列研究
- Author:
Yongzhou SHEN
1
;
Yanqin HUANG
;
Lijuan ZHU
;
Zhihao ZHANG
;
Jing YANG
Author Information
1. 314400,浙江省海宁市中医院 海宁市肿瘤防治研究所
- Keywords:
Colorectal neoplasms;
Mass screening;
Compliance;
Retrospective studies;
Incidence
- From:
Chinese Journal of Oncology
2015;(4):317-320
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the colorectal cancer incidence among compliers and non-compliers in the population of colorectal cancer screening area, and to provide scientific basis for health economic evaluation of cancer screening.Methods By screening different years build queue, to retrospectively compare the data of colorectal cancer screening from January 1, 2008 to December 31, 2013 and the data of cancer registration, and to analyze the colorectal cancer incidence rates among screening compliers and non-compliers, and to compare the average intervals between the end of screening and clinical cancer diagnosis using SPSS 19 statistical software.Mantel-Haenszel test was performed with a statistical significance level of α=0.05.Results The non-compliance rate was 38.24%among males and 28.49%among females ( P<0.001) .The non-compliance rate was highest in the 40-44 and 70-74 years age groups and lowest in the 50-59 years age group.The compliers of the screening were followed up for 476 049 person-years, and there were 51 cases of colorectal cancer, with an incidence rate of 10.71/100 000.The non-compliers of the screening were followed up for 259 183 person-years, and there were 66 cases of colorectal cancer, with an incidence rate of 25.46/100 000, which was 1.38 times higher than that of the compliance group (χ2=21.699, P<0.001).The incidence rate of colorectal cancer among subjects who were positive in initial screening but refused to receive an electronic colonoscopy was as high as 164.40/100 000, and the average delay time was 20.8±168.months.Conclusions The colorectal cancer screening adherence among women is better than among men, and that of 50-54 years and 55-59 years age groups is better than in other age groups.The subsequent incidence rate of colorectal cancer in the non-compliance group is significantly higher than that of the compliance population.
