Validity of breast-specific gamma imaging for Breast Imaging Reporting and Data System 4 lesions on mammography and/or ultrasound.
10.4174/astr.2016.90.4.194
- Author:
Min Jeng CHO
1
;
Jung Hyun YANG
;
Yeong Beom YU
;
Kyoung Sik PARK
;
Hyun Woo CHUNG
;
Young SO
;
Nami CHOI
;
Mi Young KIM
Author Information
1. Department of Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. 20110364@kuh.ac.kr
- Publication Type:Original Article
- Keywords:
Breast neoplasms;
Breast specific gamma imaging;
Mammography;
Ultrasonography
- MeSH:
Breast Neoplasms;
Breast*;
Humans;
Information Systems*;
Mammography*;
Retrospective Studies;
Sensitivity and Specificity;
Ultrasonography*
- From:Annals of Surgical Treatment and Research
2016;90(4):194-200
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The purpose of this study was to assess the breast-specific gamma imaging (BSGI) in Breast Imaging Reporting and Data System (BI-RADS) 4 lesions on mammography and/or ultrasound. METHODS: We performed a retrospective review of 162 patients who underwent BSGI in BI-RADS 4 lesions on mammography and/or ultrasound. RESULTS: Of the 162 breast lesions, 66 were malignant tumors and 96 were benign tumors. Sensitivity and specificity of BSGI were 90.9% and 78.1%, and positive predictive value and negative predictive value were 74.1% and 92.6%. The sensitivity or specificity of mammography and ultrasound were 74.2% and 56.3% and 87.9% and 19.8%, respectively. The sensitivity and specificity of BSGI for breast lesions ≤1 cm were 88.0% and 86.8%, while the values of beast lesions >1 cm were 92.7% and 61.5%. The sensitivity or specificity of BSGI and mammography for patients with dense breasts were 92.0% and 81.3% and 72.0% and 50.0%, respectively. 26 patients showed neither a nodule nor microcalcification on ultrasound, but showed suspicious calcification on mammography. The sensitivity and specificity of BSGI with microcalcification only lesion were 75.0% and 94.4%. CONCLUSION: This study demonstrated that BSGI had shown high sensitivity and specificity, as well as positive and negative predictive values in BI-RADS 4 lesions on ultrasound and/or mammography. BSGI showed excellent results in dense breasts, in lesions that are less than 1 cm in size and lesions with suspicious microcalcification only.
