One case of comprehensive treatment of acute severe ammonia-induced intoxication with extracorporeal membrane oxygenation
10.3760/cma.j.cn121094-20231103-00100
- VernacularTitle:体外膜氧合综合治疗急性重度氨气中毒1例
- Author:
Yiru SHAO
1
;
Daikun HE
;
Lianhuan JIN
;
Yu DUN
;
Jie SHEN
Author Information
1. 复旦大学附属金山医院急危重病中心，复旦大学化学伤害急危重病医学研究中心，上海市卫生健康委化学伤害急危重病医学重点实验室，上海 201508
- Keywords:
Gas poisoning;
Ammonia-induced intoxication;
Acute respiratory distress syndrome, ARDS;
Extracorporeal membrane oxygenation, ECMO;
Case report
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2024;42(9):700-704
- CountryChina
- Language:Chinese
-
Abstract:
Acute ammonia-induced intoxication is a kind of acute irritant gas poisoning, which mainly causes systemic inflammatory reaction and immune dysfunction through direct and indirect lung injury, leading to chemogenic pulmonary edema and acute respiratory distress syndrome (ARDS). The mechanism of its toxic injury is complex, and the fatality rate of patients increases significantly once ARDS occurs. In this paper, the patient with acute and severe ammonia-induced intoxication was successfully treated by extracorporeal membrane oxygenation (ECMO) combined with fiberoptic bronchoscopy and other critical technologies, and achieved good results. By analyzing the diagnosis and treatment process of severe ammonia-induced intoxication complicated with ARDS patients, this paper summarizes the clinical characteristics of ammonia-induced intoxication injury, and the application opportunities of ECMO and various critical medical technologies, so as to facilitate the efficient intervention and treatment of ammonia-induced intoxication according to the clinical opportunity and improve the survival rate of patients.
