Research progress on uranium induced human renal injury and its risk prediction
10.3760/cma.j.cn121094-20221209-00589
- VernacularTitle:铀致人体肾脏损伤及其风险预测研究进展
- Author:
Xiangming XUE
1
;
Xiaoyan WU
;
Jingming ZHAN
Author Information
1. 中国辐射防护研究院放射医学与环境医学研究所，太原 030006
- Keywords:
Uranium;
Human;
Renal injury;
Risk prediction;
Research progress
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2023;41(11):864-869
- CountryChina
- Language:Chinese
-
Abstract:
Uranium has both radiotoxicity and chemical toxicity. Low enriched uranium is mainly chemically toxic, the kidney is the target organ of uranium chemical toxicity. However, due to the differences among species and the mixed effects of chemical toxicity and radiotoxicity, the dose effect relationship of uranium is not clear, and the current standards in China do not provide chemical toxicity limits for uranium workplaces. This paper reviews the data of acute and chronic human uranium exposure, dose effect relationship and renal injury risk prediction literature at home and abroad, providing reference for the health protection of uranium workers and the establishment of chemical limits in uranium workplaces.
