The role of noninvasive hemodynamic monitoring in the evaluation of acute and severe pesticide poisoning
10.3760/cma.j.cn121094-20190829-00358
- VernacularTitle:无创血流动力学监测在急性中重度农药中毒病情评估中的作用
- Author:
Xun GAO
1
;
Mingli CHEN
;
Yufeng WANG
;
Qianqian ZHU
;
Baoyue ZHU
;
Pu WANG
;
Fantuo KONG
;
Weizhan WANG
Author Information
1. 053000 衡水，河北医科大学哈励逊国际和平医院急救医学部
- Keywords:
Hemodynamics;
Atraumatic technique;
Monitoring system;
Pesticides;
Organophosphate poisoning;
Acute paraquat pesticide poisoning (APP);
Clinical guidance;
Pr
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2020;38(12):881-885
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the method of noninvasive hemodynamic monitoring system (NICaS) in monitoring the hemodynamics of patients with acute pesticide poisoning, and to analyze the clinical guiding value of NICaS in hemodynamics of patients with severe pesticide poisoning.Methods:In August 2019, 200 patients with severe acute organophosphorus pesticide poisoning (AOPP) or moderate severe acute paraquat pesticide poisoning (APP) admitted to Harrison international peace hospital from January 2017 to August 2019 were randomly divided into NICaS group ( n=68) , transpulmonary thermodilution method ( n=67) and empirical treatment group ( n=65) . The relationship between acute physiology and chronic health score (APACHE Ⅱ) , heart rate, hemodynamic indexes, survival rate and complications were analyzed. Results:There were no significant differences in age, sex ratio, body mass index, heart rate, systolic blood pressure, no treatment period and admission APACHE II score between NICaS group, Picco group and experience group ( P>0.05) ; Compared with the experience group, the mortality of AOPP and app in NICaS group and Picco group were lower, and the differences were statistically significant ( P<0.05) .The cardiac output (CO) had a significant correlation in the interval of 2.8-6.7 L·min -1 ( r=0.738, r2=0.545, P<0.01) , and peripheral vascular resistance index (SVRI) had a significant correlation in the interval of 410-1 950 d·s·cm -5·m 2 ( r=0.792, r2=0.627, P<0.01) . Bland Altman analysis showed that CO and SVRI measured by Picco and NICaS had 97.01% and 95.52% consistency, respectively. Compared with the experience group, the average daily infusion volume and daily colloid infusion volume of NICaS group and Picco group were lower, the differences were statistically significant ( P<0.05) . Conclusion:NICaS can effectively monitor the hemodynamic indexes of patients with acute pesticide poisoning.
