Effects of acute paraquat poisoning on cognitive ability in humans
10.3760/cma.j.cn121094-20190917-00383
- VernacularTitle:急性百草枯中毒对患者认知功能的影响
- Author:
Wendi ZHANG
1
;
Xiaobei FAN
;
Bailin WU
;
Yansu GUO
;
Mengchao WANG
;
Wanyu DUAN
;
Bo SONG
Author Information
1. 050000 石家庄，河北医科大学公共卫生学院劳动卫生与环境卫生学教研室，河北省环境与人群健康重点实验室
- Keywords:
Paraquat;
Acute poisoning;
Cognitive function;
Neuropsychological tests
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2020;38(11):831-834
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of acute paraquat poisoning on cognitive function of patients through neuropsychologic test.Methods:In June 2019, 36 patients with acute paraquat poisoning in the emergency department of a provincial hospital in Hebei Province were selected as the case group. 36 healthy individuals were selected as control group. The cognitive function and depressive state were assessed by mini mental state scale, auditory word learning test, digit span test, connection test, Boston Naming Test and geriatric depression scale.Results:The results of Mini-Mental State examination showed that the total score of the case group was lower than that of the control group, the difference was statistically significant ( P<0.05) . The results of the Auditory Vocabulary Learning test showed that the scores of delayed recall, clue recall, corrective ability and semantic learning strategies of the case group were significantly lower than those in the control group ( P<0.05) . There was no significant difference in the scores of immediate memory between the two groups ( P>0.05) . The scores of Digit Span test and Boston Naming test in the control group were higher than those in the case group, the Trail Making test time in the control group was shorter than that in the case group, and the differences were statistically significant ( P<0.05) . Conclusion:Acute paraquat poisoning can impair human cognitive ability to a certain extent.
