Seroepidemiological survey and influencing factors of hepatitis E virus infection among key occupational population in Tianjin
10.3760/cma.j.cn121094-20191030-00510
- VernacularTitle:天津市重点职业人群戊型肝炎病毒感染现状及影响因素
- Author:
Ying ZHAO
1
;
Haiyan HE
;
Weishen WU
;
Guoping ZHANG
;
Zhaofei WEI
Author Information
1. 300011 天津市疾病预防控制中心
- Keywords:
Hepatitis E virus;
Antibodies;
Occupational population;
Risk factors;
Tianjin
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2020;38(7):500-503
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the infection rate and influencing factors of hepatitis E virus (HEV) among key occupational population in Tianjin, so as to help occupational population to carry out HEV prevention and control.Methods:A combination of stratified random sampling and convenience sampling was carried out for the study in Tianjin in June 2019. The livestock and poultry-related farming workers, slaughtering workers, selling workers, doctors, farmers, seafood sellers, sewage pipeline workers as the key occupational population groups (1036 person) , and non key occupational population as the control group (200 person) , cross-sectional surveys were conducted in the groups. Enzyme-linked immunosorbent assay (ELISA) was used to detect the serum IgG and IgM antibodies to HEV, and logistic regression model was used to analyze the influencing factors of HEV infection.Results:The positive rate of anti-HEV IgG in key occupational group was 26.45% (274/1036) , which was higher than that in control group of 14.50% (29/200) (χ 2=13.41, P<0.01) . The occupations with the highest positive rate of anti-HEV IgG were livestock (swine) , breeding and slaughtering workers, all of which reached 33.96% (18/53) . The difference in infection rates between different occupations was statistically significant (χ 2=22.57, P<0.01) . Multivariate logistic regression analysis showed that the longer working years, high frequency of eating out (3-5, ≥6 times/week) , drinking raw water, eating under-cooked pork or pig liver, and low frequency of washing hands were risk factors for HEV infection in occupational population ( P<0.05) . But the high education is a protective factor for HEV infection ( P<0.05) . Conclusion:There is a high positive rate of anti-HEV IgG in key occupational population in Tianjin. It is necessary to strengthen the monitoring, publicity and education of the high-risk population, pay attention to personal and dietary hygiene.
