Determination of manganese in human urine by dispersive ionic liquid-liquid microextraction-graphite furnace atomic absorption spectrometry
10.3760/cma.j.cn121094-20190718-00313
- VernacularTitle:尿中锰测定的离子液体微萃取-石墨炉原子吸收光谱法
- Author:
Yong WANG
1
;
Yingying GU
;
Ruodan FANG
;
Yong MEI
Author Information
1. 430064 武汉科技大学附属天佑医院；430065 武汉科技大学医学院公共卫生学院
- Keywords:
Ionic liquids;
Manganese;
Urine;
Spectrometry;
Dispersive liquid-liquid microextraction
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2020;38(3):216-218
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a method for the determination of manganese in urine with graphite furnace atomic absorption spectrometry (GFAAS) by using ionic liquid microextraction.Methods:The ethanol, 8-hydroxyquinoline and ionic liquid 1-octyl-3-methyl-imidazolium hexafluorophosphate were used as dispersive solvent, chelating agent and extraction solvent respectively, for the preconcentration of manganese. After the optimal extraction conditions were optimized by single factor rotations, evaluate the performance indicators such as methodological precision, accuracy, and detection limit.Results:The linear range of urine manganese was 0.0-1.6 μg/L, and the correlation coefficient of standard curve line was 0.992, the detection limit was 0.03 μg/L, the recovery of sample spiked was 84.90%-96.50%, and the relative standard deviation was 0.36%-1.84%.Conclusion:The method has the advantages of low detection limit, high recovery rate and high sensitivity. It is suitable for the determination of manganese in urine samples from occupational exposure populations and the general population.
