Research on the relationship between environmental chemical pollutant exposure and epigenetics
10.3760/cma.j.cn121094-20190621-00259
- VernacularTitle:环境化学污染物暴露与表观遗传学之间关系的研究进展
- Author:
Qingyan RUI
1
;
Xin LI
;
Hongbao ZHANG
;
Xuemei GUO
;
Na ZHENG
;
Lei ZHAO
;
Liqiong GUO
;
Penghui LI
;
Junjie YUE
Author Information
1. 300384 天津理工大学环境科学与安全工程学院
- Keywords:
Epigenetic regulation;
Environmental chemical;
Pollutants;
Exposure;
DNA methylation;
Histone modification;
miRNA
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2020;38(3):237-240
- CountryChina
- Language:Chinese
-
Abstract:
Environmental chemical pollutants are increasing, which brings various harms to human health. Epigenetics may be an important medium between exposure to environmental chemical contaminants and adverse health effects. Many environmental chemical pollutant exposures can regulate gene expression and promote disease occurrence and development through epigenetic mechanisms. This review outlines the mechanisms of epigenetics and the latest research advances in exposure and epigenetics of several environmental chemical substances (heavy metal arsenic, bisphenol A, dioctyl phthalate and benzene). To further understand and study the relationship between environmental chemical pollutant exposures and epigenetics in order to elucidate the mechanisms of disease occurrence and development.
