The assessment value of urinary NGAL combined with blood NLR in the early prognosis of patients with acute paraquat poisoning
10.3760/cma.j.issn.1001-9391.2020.02.013
- VernacularTitle:尿NGAL联合血NLR对急性百草枯中毒患者早期预后的评估价值
- Author:
Baoyue ZHU
1
;
Qingmian XIAO
;
Xun GAO
;
Wei LI
;
Yanxue DU
;
Yongjian LIU
;
Pu WANG
;
Weizhan WANG
Author Information
1. 053000 衡水，河北医科大学哈励逊国际和平医院
- Keywords:
Paraquat;
Paraquat poisoning;
Neutrophil gelatinase-related lipid carrying protein;
Neutrophils;
Lymphocytes;
Prognosis
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2020;38(2):137-140
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the evaluate of neutrophil gelatinase-associated lipocalin (NGAL) , combined with neutrophil/lymphocyte ratio (NLR) in the early prognosis of patients with acute paraquat poisoning (APP) .Methods:In March 2019, 108 APP patients admitted to Emergency Medicine Department of Hebei Medical University from January 2017 to December 2018 were selected as the observation group, 60 healthy people in the same period were see as the control group according to the results of diagnosis and 28-day survival, the observation group was divided into 51 death group and 57 survival group. The correlation between NGAL, NLR and the death of APP patients was analyzed, to explore the value of NGAL and NLR in predicting the death of APP patients.Results:Compared with the Control group, the NGAL and NLR in the observation group were significantly higher ( P<0.01) , and the NGAL and NLR in the death group were significantly higher ( P<0.05) . The results showed that NGAL and NLR were positively correlated with the death of APP patients on 28th day, and the Correlation Coefficient was 0.456 and 0.638 at 2nd Day ( P<0.01) The area under the ROC curve of NGAL, NLR and their combination were 0.764, 0.869 and 0.905, respectively. Conclusion:The combined detection of NGAL and NLR has important clinical significance in the early prediction of 28-day mortality in APP patients.
