Trabeculectomy with Mitomycin C in Congenital Glaucoma.
- Author:
In Sik LEE
1
;
Hak Sung CHUNG
;
Young Jae HONG
Author Information
1. Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Congenital glaucoma;
Mitomycin-C;
Trabeculectomy
- MeSH:
Anterior Chamber;
Endophthalmitis;
Filtration;
Follow-Up Studies;
Glaucoma*;
Humans;
Intraocular Pressure;
Mitomycin*;
Prognosis;
Retrospective Studies;
Trabeculectomy*
- From:Journal of the Korean Ophthalmological Society
1997;38(3):417-423
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We assessed the efficacy of trabeculectomy with mitomycin C in the management of congenital glaucoma of which prognosis is known to be poor. Twelve consecutive eyes of 7 primary congenital glaucoma patients who underwent trabeculectomy with mitomycin C were retrospectively reviewed. The mean age was 3.2 years(ranging from 1 to 10 years) and the mean follow-up period was 31.6 months (ranging from 15 to 42 months). The mean postoperatie intraocular pressure (IOP) at the end of follow-up period was 11.0 +/-3.0mmHg, significantly lower than the mean preoperative IOP which was 25.4 +/-6.3mmHg (P<0.01). The overall success rate was 50% after a single procedure. All the 6 failed eyes underwent the same operation again and the overall success rate was 83%. The complications included hypotony in 4 eyes (33.3%) and shallow anterior chamber in 2 eyes (16.6%), and they were all resolved spontaneously. There was no evidence of hypotonic maculopathy and endophthalmitis. Trabeculectomy with mitomycin C successfully lowered the IOP in congenital glaucoma patients without serious complication and further investigation will be required to determine ling-term effects in terms of successful filtration and possible late complications.
