Initial Mitomycin C Trabeculectomy in Young Patients.
- Author:
Yong Yeon KIM
1
;
Hai Ryun JUNG
Author Information
1. Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Juvenile primary open-angle glaucoma;
Mitomycin C;
Trabe culectomy
- MeSH:
Antimetabolites;
Endophthalmitis;
Fibroblasts;
Filtering Surgery;
Glaucoma;
Glaucoma, Open-Angle;
Humans;
Kaplan-Meier Estimate;
Mitomycin*;
Trabeculectomy*
- From:Journal of the Korean Ophthalmological Society
1997;38(3):424-429
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Antimetabolites that inhibit postoperative fibroblast proliferation increases the success of glaucoma filtration surgery. However, the use of mitomycin C in young patients has not been extensively studied. The effectiveness of initialtrabeculectomy with mitomycin C or uncomplicated glaucoma in patients age 40 years or younger was evaluated in a consecutive series of 15 eyes of 10 patients. Thirteen eyes had juvenile primary open-angle glaucoma and 2 eyes had steroid induced glaucoma. Mitomycin C (0.002%) was applied for 2 to 4 minutes during the surgery. The success rate was evaluated with Kaplan-Meier analysis, and it was 78% at postoperative 9 months. Complications included postoperative hyphema(7 eyes), hypotony (2 eyes), and bleb-related endophthalmitis.
