Prenatal diagnosis of fetal gray matter heteropia in one case and literature review

VernacularTitle:胎儿脑灰质异位的产前诊断及文献回顾
Author: Kui ZHAGN ¹ ; Shengli LI ; Huaxuan WEN ; Ying YUAN
Author Information

1. 南方医科大学附属深圳市妇幼保健院超声科
Keywords: gray matter heterotopias; prenatal diagnosis; ultrasound; magnetic resonance imaging
From: Journal of Southern Medical University 2015;(12):1770-1774
CountryChina
Language:Chinese
Abstract: Objective To investigate the prenatal ultrasonic manifestations of fetal gray matter heterotopias (FGMH) and evaluate the optimal method its prenatal diagnosis. Methods The prenatal and postnatal ultrasound images and MRI images were analyzed for a fetus with a definitive diagnosis of FGMH. The detection rates of FGMH by prenatal ultrasound and MRI reported in literature were compared. Results We identified 11 reports of FGMH from 1998 to 2015, involving 43 cases with prenatal diagnoses. Of the total of 44 cases (including our case), 32 that had been confirmed postpartum had prenatal ultrasound and MRI data, which showed a significantly lower detection rates of FGMH by prenatal ultrasound than by MRI (43.8% vs 93.8%, P<0.001). Conclusions Prenatal ultrasound can only detect subependymal heterotopia with characteristic manifestations, and the detection of other types of FGMH relies on MRI, which is currently the best option for prenatal diagnosis of FGMH.