Rituximab-induced interstitial pneumonitis:report of two cases and literature review
- VernacularTitle:利妥昔单抗相关的间质性肺炎文献复习：附2例报告
- Author:
Baohong PING
1
;
Chunyan YUE
;
Yangmin ZHU
;
Ya GAO
;
Bin WU
;
Jiaqiong HONG
Author Information
1. 南方医科大学南方医院惠侨科
- Keywords:
rituximab;
interstitial pneumonia;
lymphoma
- From:
Journal of Southern Medical University
2015;(1):129-132
- CountryChina
- Language:Chinese
-
Abstract:
We report two cases of rituximab (RTX)-induced interstitial pneumonia in two lymphoma patients receiving RTX treatment. Interstitial pneumonia was successfully managed in these two cases after a one-week-long intervention with corresponding treatments without affecting further treatment of the primary disease. RTX-induced interstitial pneumonia is characterized by a latent onset with an unclear pathological mechanism and absence of typical symptoms. High-resolution CT scan can provide valuable evidence for early diagnosis of RTX-induced interstitial pneumonia, which might be attributed partially to an increased susceptibility to P. jirovecii and fungal infection due to prolonged RTX treatment.
