Value of strain means of quantitative parameters in diagnosis of liver fibrosis
- VernacularTitle:定量参数应变均值在判定肝纤维化程度的应用
- Author:
Lifeng ZHOU
1
;
Shuzhen CONG
;
Shufang PEI
;
Yuefeng CHEN
;
Ruili ZHOU
Author Information
1. 广东省医学科学院/广东省人民医院超声科
- Keywords:
quantitative parameter of organization diffusion;
strain mean;
liver fibrosis
- From:
Journal of Southern Medical University
2014;(5):740-742
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of the strain means of the quantitative parameters of organization diffusion in determining the degree of liver fibrosis. Methods A total of 130 patients with chronic hepatitis B were examined for quantitative analysis of organization diffusion before liver biopsy to analyze the performance of the strain means in liver fibrosis of different degrees. All the cases were confirmed by pathology. Results The strain means differed significantly between different stages of liver fibrosis. Using the best cut-off values of 116.2, 111.4, 101.6 and 97.5 for diagnosis of S≥1, S≥2, S≥3 and S=4, the diagnostic sensitivities were 91.2%, 90.8%, 95.8% and 89.7%, with specificities of 90.4%, 98.6%, 93.8% and 95.6% and accuracies of 90.6%, 94.7%, 95.5% and 91.8%, respectively. Conclusion The strain mean can provide specific numerical indicators to determine the degree of liver fibrosis.