Ultrasonic radio frequency analysis technique for noninvasive evaluation of carotid arteryintima-media thickness and elasticity in patients with dyslipidemia
10.3969/j.issn.1673-4254.2014.03.11
- VernacularTitle:超声射频分析技术无创评价血脂异常患者颈动脉内中膜厚度与动脉弹性
- Author:
Yanling ZHANG
1
;
Rongqin ZHENG
;
Jinlai LIU
;
Hui ZHANG
;
Jie XU
Author Information
1. 中山大学附属第三医院超声科
- Keywords:
ultrasound;
carotid artery;
intimae-media thickness;
dyslipidemia;
arterial elasticity
- From:
Journal of Southern Medical University
2014;(3):345-348
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the value of ultrasonic radio frequency analysis technique for noninvasively evaluation of carotid artery intima-media thickness (IMT) and elasticity in patients with dyslipidemia. Methods Radio frequency quality intima-media thickness (RFQIMT) technique and radio frequency quality arterial stiffness (RFQAS) technique were used for measurement of IMT and pulse wave velocity (PWV) of the left carotid artery in 86 patients with dyslipidemia and 60 healthy volunteers. Results Apart from the patients' age, body mass index, systolic blood pressure, diastolic blood pressure, pulse pressure, total cholesterol, triglyceride, low density lipoprotein, high density lipoprotein, fasting blood glucose, IMT and PWV differed significantly between the control and case groups. IMT was positively correlated with PWV (r=0.521, P<0.05). In patients with IMT<1.0 mm (n=81), PWV differed significantly between patients with different number of other atherogenic risk factors (P=0.004), but IMT showed no such variation (P=0.079). In patients with more than 3 and those with 2 other risk factors, PWV increased significantly as compared with those with one risk factor (P=0.002). Multiple linear regression analysis showed that systolic blood pressure, age and fasting blood glucose were independently associated with PWV. Conclusion Ultrasonic radio frequency analysis technique allows accurate measurement of IMT and arterial elasticity, and may thus become a valuable method for evaluating early structural and arterial functional change of the carotid artery.