Shielding effect of distance in 131I-131 therapy for differentiated thyroid cancer
- VernacularTitle:距离在甲状腺癌患者131I治疗中的屏蔽作用
- Author:
Xiaohua CHI
1
;
Feng LIU
;
Guiping LI
;
Quanshi WANG
;
Zhifang DENG
Author Information
1. 南方医科大学南方医院核医学科
- Keywords:
differentiated thyroid cancer;
Iodine-131;
radionuclide therapy;
distance shield;
radiation protection
- From:
Journal of Southern Medical University
2014;(2):286-288
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the shielding effect of distance in radioactive iodine treatment in patients with differentiated thyroid cancer (DTC). Methods Eighty- seven DTC patients underwent postoperative radioactive iodine treatment at the therapeutic doses ranging from 2.96 GBq to 7.4 GBq. The patients were divided into two groups to receive high-dose therapy (≥3.7 GBq, 48 patients) and low-dose therapy (<3.7 GBq, 39 patients). The radiation doses at 0.05 m, 1 m, and 3 m were recorded at different days;the doses at 1 m and 3 m on the third day, the dose of standard radioactivity source of 1.11GBq 131I, and the natural background radioactivity were also recorded. Results The radiation dose at a 1-meter distance was significantly higher in the high-dose group than in the low-dose group (P<0.05). The radiation doses in different dose groups at the other distances or at different time points showed no significant differences (P>0.05). On the third day after therapy, the radiation dose at 1 m was significantly lower than the reference radioactivity source of 1.11 GBq 131I (P=0.000), but still higher than the natural background radioactivity at 3 m (P=0.000). Conclusion In DTC patients who receive radioactive iodine therapy, the radioactive radiation dose decreases rapidly after 3 days. The radioactive radiation dose on the third day is significantly lower than the reference radioactive radiation dose, so that the patients can be discharged with safety for contact at a distance beyond one meter.
