Comparison of endoscopic submucosal tunnel dissection with endoscopic submucosal dis-section for large esophageal superficial neoplasms
- VernacularTitle:内镜下隧道式与常规黏膜剥离术治疗食管大面积浅表性肿瘤的对比研究
- Author:
Yaqi ZHAI
1
;
Enqiang LINGHU
;
Huikai LI
;
Zhichu QIN
;
Xiuxue FENG
;
Xiangdong WANG
;
Hong DU
;
Jiangyun MENG
;
Hongbin WANG
;
Jing ZHU
Author Information
1. 解放军总医院消化科
- Keywords:
esophageal superficial neoplasms;
endoscopic submucosal tunnel dissection;
endoscopic submucosal dissection
- From:
Journal of Southern Medical University
2014;(1):36-40
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the safety and efficiency of endoscopic submucosal tunnel dissection (ESTD) and endoscopic submucosal dissection (ESD) for large esophageal superficial neoplasms. Methods A total of 235 consecutive patients undergoing endoscopic resection for esophageal neoplasms between October, 2010 and June, 2013 in our endoscopy center were analyzed retrospectively. According to the inclusion and exclusion criteria, 29 patients receiving ESTD or ESD for large esophageal superficial neoplasms were enrolled for data analysis. Results Of the 29 patients, 11 underwent ESTD and 18 received ESD. The dissection speed of ESTD was significantly higher than that of ESD (22.4±5.2 mm2/min vs 12.2±4.0 mm2/min, P<0.05). Despite a similar en bloc rate between the two groups (100%[11/11]vs 88.9%[16/18], P>0.05), the radical curative rate of ESTD was significantly greater than that of ESD (81.8%[9/11]vs 66.7%[12/18], P<0.05). No serious bleeding or perforation occurred in the patients except for 1 in ESD group with intraoperative bleeding, which was managed with hemostatic forceps. Eight patients had postoperative esophageal strictures in relation with circumferential extension and the longitudinal length (P<0.05). Conclusions ESTD is a safe and effective alternative for large esophageal superficial neoplasms with a shortened operative time, a higher dissection speed and a higher radical curative rate in comparison with ESD, but postoperative esophageal strictures should be closely monitored especially for lesions more than 3/4 of the circumferential extension or exceeding 50 mm.
