Changes of plasma IL-8 levels in patients with inhalation injury
10.3321/j.issn:1673-4254.2000.06.026
- VernacularTitle:吸入性损伤患者血浆IL-8水平的变化
- Author:
JIAN-Sheng ZHENG
1
;
Xiang-Dong FANG
;
Qing-Yi ZHENG
;
Jin-He CHEN
Author Information
1. 175 Hospital of PLA
- Keywords:
inhalation injury;
interleukin-8
- From:
Journal of Southern Medical University
2000;20(6):551-552
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of plasma IL-8 levels and their association with the severity of and the passage of time after inhalation injury. Methods The plasma was separated from blood samples of 27 patients 12 h, 1, 2, 4 and7 d after inhalation injury. The IL-8 level in the plasma was determined by ELISA. Result IL-8 levels were significantly increased on day 1 and kept a high level for a period over 7 d. Conclusion Inhalation injury can induce the production of IL-8, and IL-8 level is positively correlated with the by severity of inhalation injury.