Microscopic and ultrastructural features of nitric oxide synthase in rat spinal cord tissue
10.3321/j.issn:1673-4254.2000.06.002
- VernacularTitle:大鼠脊髓组织一氧化氮合酶显微及超微结构特征
- Author:
Chu-Song ZHOU
1
;
An-Min JIN
;
Da-Lie MA
Author Information
1. Zhujiang Hospital First Military Medical University
- Keywords:
nitric oxide synthase;
nitric oxide;
immunohistochemistry;
immunoelectronimicroscopy
- From:
Journal of Southern Medical University
2000;20(6):485-487
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the derivation and distribution of nitric oxide synthase (NOS) and its relation with the microvessels in the spinal cord. Methods The microscopic features and ultrastructure of NOS in the spinal cord tissue of rats were observed by immunohistochemistry and immunoelectronmicroscopy. Results NOS immunoreactive interneurons were identified mainly in the intermediolateral cell column, around the central canal and in the dorsal and ventral horn, and many of the NOS-containing neural processes and neurons were closely associated with the spinal cord microvessels. Conclusion The regional distribution of NOS may be indicative of the involvement of nitric oxide (NO) in different function related to movement, sensory processing and visceral regulation, and the ultrastructural features benefit the NO diffusion into the microvessels to regulate the blood flow in the spinal cord.
