Research progress of follistatin-related proteins in digestive system tumors
10.3760/cma.j.cn112150-20240529-00436
- VernacularTitle:卵泡抑素相关蛋白在消化系统肿瘤的研究进展
- Author:
Jianuo WU
1
;
Yuzhang JIANG
Author Information
1. 南京医科大学附属淮安第一医院检验科，淮安 223300
- Keywords:
Follistatin;
Follistatin-related proteins;
Tumor;
Digestive system;
Biomarker
- From:
Chinese Journal of Preventive Medicine
2024;58(9):1444-1449
- CountryChina
- Language:Chinese
-
Abstract:
Tumors of the digestive system are one of the most important factors affecting people′s quality of life and have become a serious public health problem globally.Early screening and intervention of tumor markers in high-risk groups for tumors is the key to tumor prevention. Follistatin-related proteins (FRP) are important members of the follistatin family and such proteins are involved in the pathological process of tumors of the reproductive system and respiratory system, among others. In recent years, FRP has attracted extensive attention in the study of digestive system tumors, suggesting that FRP may play a significant role in the development of digestive system tumors, and is a potential marker for clinical diagnosis and treatment. The article reviews the biological function, expression and potential mechanism of action of FRP associated with digestive system tumors, with a view to providing reference for the diagnosis and prevention of digestive system tumors, prognosis assessment and drug development.
