Immune-mediated neuropathies: pathophysiology and management
10.3760/cma.j.cn112150-20231220-00473
- VernacularTitle:免疫介导性周围神经病的病理生理学机制及诊疗进展
- Author:
Yuxi TIAN
1
;
Panpan YUAN
;
Xingao WANG
Author Information
1. 首都医科大学附属北京天坛医院神经内科，北京 100070
- Keywords:
Immune-mediated;
Peripheral neuropathy;
Antibodies;
Diagnosis;
Treatment
- From:
Chinese Journal of Preventive Medicine
2024;58(9):1432-1437
- CountryChina
- Language:Chinese
-
Abstract:
Immune-mediated neuropathies (IMN) are a heterogenous group of disorders affecting the peripheral nervous system, due to dysregulation of the immune system. It mainly includes Guillain-Barre syndrome, chronic inflammatory demyelinating polyradiculoneuropathy, multifocal motor neuropathy and so on. Most of these diseases can be clinically improved by appropriate immunotherapy, but some patients still have unsatisfactory results. Therefore, studying the pathophysiology of the occurrence and development of diseases can reveal the nature of diseases and provide a theoretical basis for the prevention, diagnosis and treatment of diseases. In this paper, the pathophysiological mechanism of various IMNs is described in detail, with emphasis on immunological mechanism, and the progress of diagnosis and treatment of various IMNs is briefly introduced.
