Research progress on antibody index in the diagnosis and treatment of central nervous system diseases
10.3760/cma.j.cn112150-20231113-00338
- VernacularTitle:抗体指数在中枢神经系统疾病诊疗中的研究进展
- Author:
Sirui WU
1
;
Yuanfang WANG
;
Dongdong LI
Author Information
1. 四川大学华西医院实验医学科，成都 610041
- Keywords:
Central nervous system diseases;
Antibody index;
Intrathecal specific antibody
- From:
Chinese Journal of Preventive Medicine
2024;58(8):1197-1203
- CountryChina
- Language:Chinese
-
Abstract:
Cerebrospinal fluid (CSF) laboratory tests are important for diagnosing central nervous system (CNS) diseases. Research on intrathecal immunoglobulin-related indexes has gradually attracted attention. The antibody index, which corrects for the effect of individual blood-brain barrier function on CSF antibody test results, is of great significance in the differential diagnosis, efficacy monitoring and prognostic assessment of CNS diseases. It is expected to become a new index for the diagnosis of CNS diseases. This article reviews the concept of antibody index and the research progress of differential diagnosis and treatment of various CNS diseases in order to provide references for the diagnosis, efficacy monitoring and disease progression assessment of CNS diseases.
