Epidemiological characteristics of human respiratory syncytial virus among acute respiratory infection cases in 16 provinces of China from 2009 to 2023
10.3760/cma.j.cn112150-20231213-00440
- VernacularTitle:2009—2023年中国16个省份急性呼吸道感染病例中人呼吸道合胞病毒的流行特征分析
- Author:
Aili CUI
1
;
Baicheng XIA
;
Zhen ZHU
;
Zhibo XIE
;
Liwei SUN
;
Jin XU
;
Jing XU
;
Zhong LI
;
Linqing ZHAO
;
Xiaoru LONG
;
Deshan YU
;
Bing ZHU
;
Feng ZHANG
;
Min MU
;
Hui XIE
;
Liang CAI
;
Yun ZHU
;
Xiaoling TIAN
;
Bing WANG
;
Zhenguo GAO
;
Xiaoqing LIU
;
Binzhi REN
;
Guangyue HAN
;
Kongxin HU
;
Yan ZHANG
Author Information
1. 传染病溯源预警与智能决策全国重点实验室 国家卫生健康委医学病毒和病毒病重点实验室 中国疾病预防控制中心病毒病预防控制所，北京 102206
- Keywords:
Human respiratory syncytial virus;
Acute respiratory infections;
Epidemiological characteristics;
Surveillance
- From:
Chinese Journal of Preventive Medicine
2024;58(7):945-951
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the epidemiological characteristics of human respiratory syncytial virus (HRSV) among acute respiratory infection (ARI) cases in 16 provinces of China from 2009 to 2023.Methods:The data of this study were collected from the ARI surveillance data from 16 provinces in China from 2009 to 2023, with a total of 28 278 ARI cases included in the study. The clinical specimens from ARI cases were screened for HRSV nucleic acid from 2009 to 2023, and differences in virus detection rates among cases of different age groups, regions, and months were analyzed.Results:A total of 28 278 ARI cases were enrolled from January 2009 to September 2023. The age of the cases ranged from<1 month to 112 years, and the age M ( Q1, Q3) was 3 years (1 year, 9 years). Among them, 3 062 cases were positive for HRSV nucleic acid, with a total detection rate of 10.83%. From 2009 to 2019, the detection rate of HRSV was 9.33%, and the virus was mainly prevalent in winter and spring. During the Corona Virus Disease 2019 (COVID-19) pandemic, the detection rate of HRSV fluctuated between 6.32% and 18.67%. There was no traditional winter epidemic peak of HRSV from the end of 2022 to the beginning of 2023, and an anti-seasonal epidemic of HRSV occurred from April to May 2023. About 87.95% (2 693/3 062) of positive cases were children under 5 years old, and the difference in the detection rate of HRSV among different age groups was statistically significant ( P<0.001), showing a decreasing trend of HRSV detection rate with the increase of age ( P<0.001). Among them, the HRSV detection rate (25.69%) was highest in children under 6 months. Compared with 2009-2019, the ranking of HRSV detection rates in different age groups changed from high to low between 2020 and 2023, with the age M (Q1, Q3) of HRSV positive cases increasing from 1 year (6 months, 3 years) to 2 years (11 months, 3 years). Conclusion:Through 15 years of continuous HRSV surveillance analysis, children under 5 years old, especially infants under 6 months old, are the main high-risk population for HRSV infection. During the COVID-19 pandemic, the prevalence and patterns of HRSV in China have changed.
