Furry animal allergen components diagnosis: identification of main components and clinical management strategies
10.3760/cma.j.cn112150-20240403-00274
- VernacularTitle:毛皮动物过敏原组分诊断:主要组分鉴别及临床管理策略
- Author:
Zhifeng HUANG
1
;
Aoli LI
;
Huiqing ZHU
;
Ziyu YIN
;
Baoqing SUN
Author Information
1. 广州医科大学附属第一医院临床检验中心,呼吸疾病全国重点实验室,国家呼吸医学中心,国家呼吸系统疾病临床研究中心,广州呼吸健康研究院,广州 510120
- Keywords:
Furry animals;
Component‐resolved diagnosis;
Animal allergy;
Specific IgE
- From:
Chinese Journal of Preventive Medicine
2024;58(6):931-940
- CountryChina
- Language:Chinese
-
Abstract:
Furry animal allergens, particularly cat and dog hair and dander, are common allergens in indoor environments, affecting the health of people world widely. Key sensitizing components such as Fel d 1 from cats and Can f 1 from dogs have been extensively studied and identified by the scientific community. Component resolved diagnosis (CRD) technology in modern diagnostic methods provides an accurate way to identify and distinguish these components, which is extremely important for the prevention of furry animal allergies and the formulation of personalized treatment strategies. To enhance the understanding of furry animal component diagnosis and promote the alignment of the Chinese discipline of allergology with international standards, this article interprets and explains the content of the "Molecular Allergology User′s Guide 2.0" recently released by the European Academy of Allergy and Clinical Immunology. It focuses on the epidemiological characteristics of furry animal components, the diversity of allergen protein families, and their clinical diagnosis and management.