Research progress on the effects of exposure to major persistent organic pollutants during pregnancy on the functional development of nervous system in children

VernacularTitle:孕期主要持久性有机污染物暴露对儿童神经系统功能发育影响的研究进展
Author: Shuqi WU ¹ ; Borui LIU ; Zhe YANG ; Lu ZHENG ; Xiaochuan WANG ; Xinyue YANG ; Lihong JIA ; Jiajin HU
Author Information

1. 辽宁省肥胖与糖脂代谢性疾病重点实验室　中国医科大学健康科学研究院，沈阳　110122
Keywords: Persistent organic pollutants; Nervous system function; Child development; Intrauterine exposure; Review
From: Chinese Journal of Preventive Medicine 2024;58(6):917-923
CountryChina
Language:Chinese
Abstract: Persistent Organic Pollutants (POPs) have the characteristics of resistance to environmental degradation, bioaccumulation and long-distance migration potential. Maternal exposure to POPs during pregnancy can enter the fetal blood circulation through the placental barrier, and have a potential impact on the functional development of the nervous system of the offspring. This in turn leads to the occurrence and development of neurological defects and diseases in adulthood. The purpose of this paper is to elucidate the effects of exposure to three major POPs (organochlorine compounds, perfluoroalkyl and polyfluoroalkyl substances, and polybrominated diphenyl ethers) during pregnancy on the functional development of the nervous system (social emotions, cognition, language, exercise, and adaptability) in children, and to provide reference for subsequent studies.