The advances on oral tolerance induction for prevention of egg allergy in infants
10.3760/cma.j.cn112150-20231108-00323
- VernacularTitle:口服耐受诱导疗法预防婴幼儿鸡蛋过敏的研究进展
- Author:
Yuanyuan CHAI
1
;
Hua QIAN
Author Information
1. 苏州大学附属儿童医院皮肤科，苏州 215000
- Keywords:
Egg allergy;
Oral tolerance induction;
Efficacy;
Safety
- From:
Chinese Journal of Preventive Medicine
2024;58(6):763-767
- CountryChina
- Language:Chinese
-
Abstract:
The prevalence of food allergy is increasing worldwide and seriously affects the living quality of patients and their families. Egg allergy is one of the commonest forms of food allergy. The traditional regimen is to delay the introduction of eggs to infant complementary foods, which is not able to reduce the prevalence of egg allergies and causes negative effects on infants′ physical and psychological conditions. Oral tolerance therapy is an approach to establish immune tolerance by the active suppression of specific immune responses to antigens in the gastrointestinal tract. The development of oral tolerance through early introduction of eggs to infant complementary has proven effective in randomized controlled trials, which has been incorporated into infant feeding guidelines in many countries. This article focuses on the mechanism, efficacy and safety of oral tolerance induction in the prevention of egg allergy.
