The management mode of hereditary angioedema: intra-hospital multi-diciplinary treatment, linkage of cooperation network, online and offline whole process management
10.3760/cma.j.cn112150-20231123-00371
- VernacularTitle:遗传性血管性水肿诊治的“院内多学科会诊协作网联动线上线下全程管理”模式的初探
- Author:
Wo YAO
1
;
Dingqian WU
;
Ying SHEN
;
Lei SHEN
;
Yan LI
;
Liuya GE
;
Songzhao ZHANG
;
Jiong CHEN
;
Huiying WANG
Author Information
1. 浙江大学医学院附属第二医院变态反应科，杭州 310009
- Keywords:
Hereditary angioedema;
Management mode;
Clinical pathway;
C1 esterase inhibitor
- From:
Chinese Journal of Preventive Medicine
2024;58(3):406-413
- CountryChina
- Language:Chinese
-
Abstract:
Hereditary angioedema (HAE) is an autosomal dominant inherited disease characterized by recurrent and unpredictable episodes of subcutaneous or submucosal edema. These attacks could induce fatal risk when larynx is involved. The estimated prevalence of HAE is about 1 in 50 000. Due to its rarity and the diversity of clinical manifestations, HAE is known little by related physicians and misdiagnosis and mistreatment happens very often. Therefore, it is crucial to improve physicians′ understanding of HAE. To address this, a comprehensive management approach for the diagnosis and treatment of HAE have developed in our hospital. This approach includes intra-hospital multi-disciplinary treatment (MDT), collaboration with provincial network hospitals, patient education online and offline interacting with media propaganda. By implementing this approach, the diagnostic precision was significantly improved, the diagnostic time was significantly shortened, and the frequency of emergency interventions for severe laryngeal edema was significantly reduced. Additionally, the collection of data from HAE patients has provided valuable clinical insights for the diagnosis and treatment of HAE in China.
