Analysis of saliva cotinine and 3′-hydroxynicotinine concentration levels among restaurant workers in six cities of China
10.3760/cma.j.cn112150-20210209-00144
- VernacularTitle:中国六城市餐饮场所工作人员唾液可替宁和三羟基可替宁浓度水平比较
- Author:
Zhaobin QI
1
;
Lin XIAO
;
Jiali DUAN
;
Jingfan XIONG
;
Kunlei LE
;
Yu SONG
;
Hongyan WANG
;
Jianan DAI
Author Information
1. 中国疾病预防控制中心控烟办公室，北京100050
- Keywords:
Tobacco smoke pollution;
Cotinine;
Cross-sectional studies;
3′-Hydroxycotinine
- From:
Chinese Journal of Preventive Medicine
2021;55(12):1482-1485
- CountryChina
- Language:Chinese
-
Abstract:
This study was conducted between November to December 2020, consisting of six representative cities, Beijing, Shanghai, Shenzhen (with comprehensive smoke-free legislation), and Changsha, Chongqing, Shenyang (without comprehensive smoke-free legislation), 678 subjects were enrolled eventually, the mean age of the 678 subjects was (35.61±12.91)years old. Subjects from cities with comprehensive smoke-free legislation accounted for 49.71% of the total; male subjects accounted for 19.47%; meanwhile subjects from large, medium, and small restaurants accounted for 13.57% (92), 37.32% (253) and 49.11% (333) respectively. The analysis results indicate that the positive rate of restaurants staff of cotinine and 3′-hydroxynicotinine was lower in cities with comprehensive smoke-free legislation(34.12% vs 68.04%, χ2=78.01, P<0.001; 16.32% vs 41.94%, χ2=53.79, P<0.001), with staff from cities with comprehensive smoke-free legislation have lower concentrations of cotinine and 3′-hydroxynicotinine than their counterparts from cities without comprehensive smoke-free legislation(0.250 ng/ml vs 0.742 ng/ml, P<0.001; 0.250 ng/ml vs 0.250 ng/ml, P<0.001). No statistically significant difference in the concentration of cotinine and 3′-hydroxynicotinine in saliva between staff from restaurants of different sizes was detected ( P>0.05).
