The risk factors of first recurrence in ischemic stroke patients in different periods after first attack
10.3760/cma.j.cn112150-20210719-00689
- VernacularTitle:缺血型卒中患者首次发病后不同时期内的复发危险因素研究
- Author:
Jian GUO
1
;
Tianjia GUAN
;
Longde WANG
;
Baohua CHAO
;
Yuanli LIU
Author Information
1. 中国医学科学院北京协和医学院 北京协和医院心内科 医学科学研究中心 100730
- Keywords:
Ischemic stroke;
Recurrence;
Risk factor
- From:
Chinese Journal of Preventive Medicine
2021;55(9):1105-1113
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the risk factors of first recurrence in ischemic stroke patients at different periods after first attack.Methods:The subjects were from the screening population of China National Stroke Screening Survey (CNSSS) from 2013 to 2015. The basic demographic information, stroke history, influencing factors and modified Rankin Scale (mRs) scores were collected by using standardized face-to-face questionnaires. A case-control study was conducted to investigate the risk factors of first recurrence in ischemic stroke patients who relapsed for the first time within 12 months, 24 months and 36 months as the case group and non-recurrent ischemic stroke patients as the control group. Further, the subjects were stratified into different subgroups by age, gender and urban-rural distribution to investigate the risk factors of first recurrence in different periods.Results:Diabetes ( OR=1.71, 95% CI: 1.08-2.71) and coronary heart disease ( OR=1.55, 95% CI: 1.09-2.19) were significantly associated with the risk of first recurrence within 12 months after the first onset of ischemic stroke. The diabetes was significantly associated with the risk of first recurrence within 24 months ( OR=1.94, 95% CI: 1.33-2.83) and 36 months ( OR=1.64, 95% CI: 1.15-2.34) after the first onset of ischemic stroke. With the increase of mRs score, the risk of first recurrence within 12 months, 24 months and 36 months in ischemic stroke patients increased significantly. In the same period, the risk factors of ischemic stroke recurrence differed in patients with different age, gender and urban-rural distribution. Conclusions:The risk factors of first recurrence in ischemic stroke patients are diverse at different periods after the first onset of ischemic stroke. In different subgroups, the risk factors of first recurrence and the strength of its corresponding association are also different.
